Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,786
Tocris Bioscience™ MLS 1547
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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G protein-biased D2 partial agonist
| CAS | 315698-36-3 |
|---|---|
| Chemical Name or Material | 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H19ClN4O |
| Formula Weight | Observed MW: 354.83 |
| Assay Percent Range | >98% |
1,787
Tocris Bioscience™ TG 003
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CAS: 719277-26-6 Molecular Formula: C13H15NO2S
| CAS | 719277-26-6 |
|---|---|
| Molecular Formula | C13H15NO2S |
1,788
Tocris Bioscience™ NH 125
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CAS: 278603-08-0 Molecular Formula: C27H45IN2
| CAS | 278603-08-0 |
|---|---|
| Molecular Formula | C27H45IN2 |
1,789
Tocris Bioscience™ Linsitinib
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Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor
| Target | IGF-I R/IGF1R |
|---|---|
| CAS | 867160-71-2 |
| Purity | 0.98 |
| Chemical Name or Material | cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H23N5O |
1,790
Tocris Bioscience™ Trametinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective MEK inhibitor; orally bioavailable
| Target | MEK Inhibitors |
|---|---|
| CAS | 871700-17-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H23FIN5O4 |
1,791
Tocris Bioscience™ AZ' '9567
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Potent MAT2a (methionine adenosyltransferase 2a) inhibitor
1,792
Tocris Bioscience™ Ro 61-8048
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CAS: 199666-03-0 Molecular Formula: C17H15N3O6S2
| CAS | 199666-03-0 |
|---|---|
| Molecular Formula | C17H15N3O6S2 |
1,793
Tocris Bioscience™ PHTPP
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CAS: 805239-56-9 Molecular Formula: C20H11F6N3O
| CAS | 805239-56-9 |
|---|---|
| Molecular Formula | C20H11F6N3O |
1,794
Tocris Bioscience™ Ciclopirox
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Pan-histone demethylase inhibitor
| CAS | 29342-05-0 |
|---|---|
| Chemical Name or Material | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C12H17NO2 |
| Formula Weight | Observed MW: 207.27 |
| Assay Percent Range | >99% |
1,795
Tocris Bioscience™ TC-E 5002
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Selective KDM2/7 inhibitor
| Inhibitors | TC-E 5002 |
|---|---|
| Product Type | TC-E 5002 |
| Molecular Weight (g/mol) | 285.38 |
| Purity | >98% |
1,796
Tocris Bioscience™ TBB
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CAS: 17374-26-4 Molecular Formula: C6HBr4N3
| CAS | 17374-26-4 |
|---|---|
| Molecular Formula | C6HBr4N3 |
1,797
Tocris Bioscience™ CIM 0216
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Selective TRPM3 agonist
| Target | TRPM Agonists |
|---|---|
| CAS | 1031496-06-6 |
| Purity | >98% |
| Chemical Name or Material | 3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C21H21N3O2 |
| Formula Weight | 347.41 |
1,798
Tocris Bioscience™ MI 14
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Potent and selective PI 4-kinase IIIβ inhibitor
1,799
Tocris Bioscience™ Topiramate
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GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV
| Inhibitors | Topiramate |
|---|---|
| Product Type | Topiramate |
| Molecular Weight (g/mol) | 339.36 |
| Purity | >99% |
1,800
Tocris Bioscience™ BI 9321
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Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain